Progress Update June

I’m particularly proud of how smoothly our MDIP project has been progressing. As of June 2025 we have received over two-thirds of the medications data in scope of our project, and we’ve successfully uploaded these to our database. We have also begun the preliminary matching of our medications indexes to known pharmacogenomic flags, and the results are quite impressive so far.

• Ingested medications indexes from medications regulators: 21
• Total number of medications held in database as of June 2025: 530,812
• Total number of PGx linked medications: 147,331

Interesting findings so far:

• Although over half a million medications are now present in the system, many medications are sold across multiple countries, so national medications indexes hold many of the same drugs. We have not yet calculated the number of unique medications by name.
• There is wide variety in the numbers of listed medications per market. Many countries in Europe list fewer than 10,000 medications (Ireland, Luxembourg, Malta, Croatia and Estonia are examples), while other countries have greater than 40,000 medications listed (Hungary, Slovakia, Belgium and the Czech Republic)
• Most countries in scope provide data extracts relatively conveniently, although significant work is necessary to ingest them to a single database.
• Approximately half of EU regulatory bodies responded back to requests, although of the remainder who did not respond, data was already published online. 7 countries were contacted a second time, either for insufficient data or no data, for which we await a response.

Work continues to progress on our final website and searchable database as we enter the final phase of the project.